The Ion Proton System has been designed with affordability in mind. The system combines semiconductor sequencing technology with biochemistry to directly translate chemical information into digital data. This eliminates the need for expensive optics and complex sequencing chemistries, resulting in a sequencing system that is highly-affordable to own and operate.
Applications:
ChIP sequencing
Exome sequencing
Gene expression sequencing
De novo sequencing
Small RNA sequencing
Whole transcriptome sequencing
Accurate high-throughput sequencing
The Ion Proton System reduces the high cost and complexity of high-throughput sequencing, bringing it to your lab on your schedule.
Affordable sequencing for all
The Ion Proton System has been designed with affordability in mind. The system combines semiconductor sequencing technology with biochemistry to directly translate chemical information into digital data. This eliminates the need for expensive optics and complex sequencing chemistries, resulting in a sequencing system that is highly-affordable to own and operate.
Scalable, flexible throughput
Chip-based semiconductor sequencing enables you to scale your runs to your research needs. The Ion PI Chip provides you with 4080 M reads, enabling you to sequence 13 human exomes or 18 human transcriptomes per run.
Fast, simple workflows
The Ion Proton System offers a complete workflow from sample through analysis, and variant calling or RNA analysis. It may beused with the Ion Chef System to enable automated, high-throughput template preparation and reproducible chip loading. Built for speed, the Ion Proton System provides fast sequencing run times, taking you from DNA to variants in a single day. It is equipped with Ion Reporter Software, providing integrated tools for tertiary data analysis for DNA variation analysis across single, paired, or trio research samples.
*Includes:
Dell PowerEdge T620 Tower Server
Specifications:
Working environment (for indoor use only)Temperature: 68-77 F (20-25 C)
Humidity: 40-60%, noncondensing
Altitude: <6,500 ft (2,000 m)
Clearances:
12 in (30.5 cm) in rear
4 in (10 cm) on left side
4 in (10cm) on right side
4 in (10 cm) from front edge of bench to sequencer bezel
36 in (90 cm) aisle in front of bench for operator access
Optional rack mounting with two Ion Proton Sequencers per rack
Gas Supply Connection: 0.25 in push-to-connect fitting
Pressure: 30 psi
Composition: nitrogen (grade 4.8, 99.998% or better)
Other connections Ethernet: 1 GigE
USB: 2x USB 2.0
Power:
Voltage: 100 V (min) to 240 V (max)
Current: 14 A (max)
Frequencing: 50/60 Hz
Power Draw: 1,350 W
Dimensions:
Width: 21.3 in/54.2 cm
Depth: 30.5 in/77.5 cm
Height: 18.7in/47.4 cm
WeightCrated for shipment: 200 lb/90.7 kg
Free-standing: 130 lb/59 kg
Ion Proton System performance specifications with Ion PI Chip:
Throughput: Up to 15 Gb
Read length: Up to 200-base fragment reads
Number of reads passing filter: 60-80 million reads passing filter
Sequencing run time 2.5 hours
Barcoding solutions 384 barcodes supported by Torrent Suite Software
96 off-the-shelf barcodes for DNA
16 off-the-shelf barcodes for RNA
Software solutions
Torrent Suite Software utilizing Torrent Browser including TMAP alignment and Torrent Variant Caller for germline or somatic mutation detection.
Torrent Browser (included) offers users remote web access to instrument status monitoring, run quality reports, individual data files, and extensible plug-ins for application-specific analysis.
Plugins available for download from the Torrent Browser Plugin Store for analysis of genome sequencing, targeted sequencing, variant analysis and annotation, microbial sequencing, transfer to 3rd party bioinformatics packages, and more.
Data can optionally flow into Ion Reporter Software for controlled analysis, annotation, and reporting of variants. Ion Reporter Software provides application specific workflows to support single, trio and paired tumor normal analysis.
Data formats:
Industry standard FASTQ, SFF, BAM and VCF format outputs
Chip Compatibility
ChipIon PI v3 Chip
Reads 60-80M
Run time (hrs.) ~2.5
Additional Prep Fees May Apply
