The Quattro Micro API is a high performance triple quadrupole spectrometer designed for routine LC/MS/MS operation. The instrument may be coupled to the following liquid introduction systems: HPLC system, to provide molecular weight information from an LC run or to perform target analysis and quantification. Syringe pump, for analysis of precious, low concentration compounds. Sample ionization take splace in the source at atmospheric pressure. These ions are sampled through a series of orifices into the first quadrupole where they are filtered according to their mass to charge ratio (m/z). The mass separated ions then pass into the hexapole collision cell where they either undergo collision induced decomposition (CID) or pass unhindered to the second quadrupole. The fragment ions are then mass analyzed by the second quadrupole.
Features:
Accurate, reproducible chromatographic peak area measurement
Robust ZSpray atmospheric pressure ionization interface
Versatile range of ionization options
Multimode capability in a single run
Automated instrument optimization and quantitative method development tools
Dedicated application managers for your specialized analytical requirements
Small footprint that sits easily on your laboratory benchtop
Manufacturer Specification
Acquisition rates up to5000 amu/sec
2040 amu upper mass limit.
Quattro Micro LC-MS/MS has vertically mounted liquid inlet probes to minimize tube length and peak dispersion.
Electrospray Positive Ion
Measured signal/noise ratio obtained from the chromatogram monitoring the transition m/z 609 m/z 195 on injection of 10pg (16fmol) of reserpine will be >20:1.
10l of a 1 pg/l reserpine solution in 50/50 acetonitrile/water (no additives) will be injected at a flow rate of 200 l/min, in MRM mode, 1 second dwell, span 0Da. The resolution of the ion at m 609 will be <1Da peak width at half height (MS1 and MS2).
Electrospray Negative Ion
The signal/noise ratio measured on the [M-H]- peak at m/z 503 from a sample consumption of 10ng raffinose will be >100:1.
A solution of 5 ng/l Raffinose in 50/50 acetonitrile/water (no additives) will be introduced at a flow rate of 10 l/min and the summation of two 6 second scans over the mass range m/z 100-600 represents a total sample consumption of 10ng.
APcI Positive Ion
Measured signal/noise ratio obtained from the mass chromatogram of m/z 609 in SIR mode on direct injection of 10pg (16fmol) reserpine (10l injection of a 1pg/l solution) at a flow a rate of 1ml/min will be >10:1.
Additional Prep Fees May Apply
