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Item Details

Item specification details
Property Value
Item Id 400957
Item #: 400957
Item: THERMO ELECTRON Transfer Dissociation for LTQ Series Mass Specs
Model #: N/A
Serial #: N/A
Year Built: N/A
Location: California
Price: $1,499.00

Description

Electron Transfer Dissociation (ETD)

Achieve better analysis of proteins and their post-translational modifications (PTMs) with the Thermo Scientific Electron Transfer Dissociation (ETD) option. Unlike CID, which cleaves weakly bound modifications off the peptide backbone, ETD induces fragmentation along the peptide backbone in a sequence-independent manner, leaving labile modifications linked to the peptide chain. This greatly simplifies identification of modification sites. ETD produces primarily c- and z-type fragment ions that complement the b- and y-type ions produced by CID, increasing sequence coverage and protein IDs.

Electron transfer dissociation is a supremely useful tool for the analysis of post-translationally modified proteins. ETD capability can be added to many Thermo Scientific ion trap and Orbitrap mass spectrometers. Thermo Scientific Proteome Discoverer software includes unique capabilities to help users take full advantage of the information provided by ETD.

ETD preserves labile PTMs, allowing straightforward identification of the peptide sequence and the site of modification

For top-down analysis, ETD can be combined with proton transfer reaction (PTR) which dramatically simplifies spectra from intact proteins

For workflows that include low-mass isobaric mass tags, ETD can be combined with pulsed-Q dissociation (PQD) which eliminates the normal low-mass cutoff

ETD can be added to most Thermo Scientific LTQ-series ion trap and hybrid ion trap-Orbitrap mass spectrometers

Proteome Discoverer software includes the proprietary Z-Core database search algorithm specifically optimized for ETD spectra

Proteome Discoverer software can easily merge complementary CID and ETD results to maximize protein sequence coverage

**Unit sold (AS/IS) as a part, this needs to be connected to LTQ in order to work**

Additional Prep Fees May Apply

Shipping

Item shipping dimensions and specifications
Dimension Measurement
Height: 27.00 in
Width: 30.00 in
Length: 11.00 in
Weight: 78.00 lbs
Prep Fee: N/A
Registered Customers can request shipping quotes free of charge. Shipping Quotes take 1-3 Business Days to Process

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