Waters Acquity UPLC I-CLass Plus with Xevo TQ-S Micro IVD System
***This system was tested to specifications. This system is less than one year old. It was only ever turned on for IQ/OQ validation and never used for anything else. System will need to be validated/calibrated to ensure optimal results. Everything pictured included, (Lab table for display purposes only.) 30-day warranty included with purchase. See photos for details.
(Please be advised that any warranty/guarantee/return policy provided from the seller is between the buyer and the seller only. Bid on Equipment is not and cannot be held responsible in any way. Please reference our Terms and Conditions for further information.)
Includes:
Xevo TQ-S Micro Mass Spectrometer 186007833IVD with Z Spray Ion Source ESI,APCI,ESCi
Acquity UPLC-FTN H Class Plus Sample Manager FTN E22USM325M
Acquity I UPLC Binary Solvent Manager 186015046IVD
Acquity UPLC Column Manager 186015042IVD
Peak Genius XE35 Nitrogen Generator
Leybold Sogevac SV40BIFC
PowerVar Security Plus UPS ABCDEF3000-22
Increase capabilities in the clinical laboratory
Achieving consistently low levels of quantification with the most complex of biological sample matrices can often be a challenge.
Ensure accurate routine low concentration analyte quantification with the robust, sensitive, and compact ACQUITY UPLC I-Class PLUS/Xevo TQ-S micro IVD System. With this flexible LC-MS/MS system, you can achieve superior performance per square inch and exceptional analytical flexibility.
Overview
Expand testing capabilities with a wide dynamic range all while achieving reproducible low levels of quantification for difficult analysis
Control user access, monitor your system, and efficiently process and review your results with intuitive informatics software solutions
Ensure minimal instrument downtime with a simple tool-free maintenance and cleaning procedures
Enhance the end-to-end workflow with seamless software integration to liquid handling robots and third-party LIMS providers through Waters informatics solutions
Maintain system uptime withFlexCHOICE: mySystem Coverage Solutions, providing priority on-site support, 2-hour call back and 48-hour on-site response
Recommended Use:Ideal for routine and low concentration analyte quantification in the clinical laboratory environment.
High performance from a compact design with rapid, reliable, and reproducible quantitative data for the clinical laboratory
A revolutionary tandem quadrupole design for small spaces, delivering consistent low levels of quantitation with a wide dynamic range, providing:
Robust performance for reproducible detection of analytes at low levels in complex biological liquid sample matrices
Confidence to quantify more analytes using high acquisition rates
Accessible sensitivity and method transfer with the Xtended Dynamic Range (XDRTM) detector
Understand sample complexity and improve method development with RADARTM
Clinical laboratories now have access to the selectivity, sensitivity, and versatility of LC-MS/MS analysis not seen using traditional techniques
Waters follows international quality standards with respect to its medical devices
Robust performance from a compact design for clinical laboratories
Robust performance begins in the source with ZSprayTMgeometry, efficiently removing neutral molecules while drawing ions through the sample cone into the analyzer. The StepWaveTMion guide in the XevoTQ-S micro is designed to cope with the challenges in the modern clinical laboratory that are produced by high sample throughput and difficult matrices.
Neutrals and gas load are passively removed for enhanced transmission with the ions actively transferred into the mass analyzer, improving sensitivity and robustness. All this is achieved while maintaining an extremely small footprint due to the class-leading compact design of the Xevo TQ-S micro.
Acquire data points faster without without loss in sensitivity
Xccelerated Ion Transfer (XITTM) electronics, using SpaceWire technology allow this instrument to acquire data at extremely high speeds without compromising performance. The next generation T-WaveTMcollision cell permits acquisition of 500 MRM channels/s whilst minimizing cross-talk and maintaining intensity. The increased MS full scan speed capability of up to 20,000 Da/s reduces the impact on the duty cycle when rapidly switching between MS full scan and MS/MS acquisition (RADAR and PICs).
In addition, fast polarity switching gives coverage of positive and negative ionizing compounds in a single injection. Maintaining performance at these speeds is critical as every clinical laboratory requires high quality data that is reproducible to enable reliable quantification. Method transfer is now even easier with the advanced XDR detector which provides unique Xtended Dynamic Range improving usability with low limits of detection.
Understanding sample complexity in clinical LC-MS/MS method development
Challenges for quantitative methods include:
Performing targeted analysis for analytes of interest and detecting unexpected analytes in the same injection
Characterization of background matrix for every sample throughout each run to improve data quality
Examining matrix background during method development to better characterize targeted methods for interferences as well as ion enhancing and ion suppressing species
These challenges may be overcome by using RADAR which is the ability to obtain full scan (MS) and MRM (MS/MS) data simultaneously.
Comprehensive data processing with uncomplicated results review
Ready access to quantitative data and rapid review of data is essential in any clinical laboratory. The TargetLynx XS Application Manager provides even more functionality, as well as the ability to perform standard addition to accurately calculate analyte concentrations. Building upon Waters flagship quantitative analysis package, the TargetLynx XS Application Manager provides ready access to quantitative data which is essential to any clinical laboratory. Years of iterative design have lead to an efficient workflow that supports rapid data review and reporting tools to ensure results reach their destinations as smoothly and as quickly as possible.
Ion source flexibility comes as standard
Universal ion source architecture ensures coverage of every application, with unlimited potential. The Xevo range of mass spectrometers all have multiple ion source options which are interchangeable in minutes and provide optimal ionization for each function required in the laboratory. The Xevo TQ-S may be used with ESI, ESCI, APCI, APGC, ASAP, nanoflow ESI and ionKey and is also compatible with DESI (Prosolia), DART (IonSense) and LDTD (Phytronix) ion sources.
Additional Prep Fees May Apply
